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Autolysin-mediated peptidoglycan hydrolysis is required for the surface display of Staphylococcus aureus cell wall-anchored proteins.
Proc Natl Acad Sci U S A. 2023 Mar 21;120(12):e2301414120. doi: 10.1073/pnas.2301414120. Epub 2023 Mar 15.
Proc Natl Acad Sci U S A. 2023.
PMID: 36920922
Free PMC article.
A genetic platform to investigate the functions of bacterial drug efflux pumps.
Teelucksingh T, Thompson LK, Zhu S, Kuehfuss NM, Goetz JA, Gilbert SE, MacNair CR, Geddes-McAlister J, Brown ED, Cox G.
Teelucksingh T, et al. Among authors: gilbert se.
Nat Chem Biol. 2022 Dec;18(12):1399-1409. doi: 10.1038/s41589-022-01119-y. Epub 2022 Sep 5.
Nat Chem Biol. 2022.
PMID: 36065018
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The steroid side-chain-cleaving aldolase Ltp2-ChsH2DUF35 is a thiolase superfamily member with a radically repurposed active site.
Aggett R, Mallette E, Gilbert SE, Vachon MA, Schroeter KL, Kimber MS, Seah SYK.
Aggett R, et al. Among authors: gilbert se.
J Biol Chem. 2019 Aug 2;294(31):11934-11943. doi: 10.1074/jbc.RA119.008889. Epub 2019 Jun 16.
J Biol Chem. 2019.
PMID: 31209106
Free PMC article.
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A Key Glycine in Bacterial Steroid-Degrading Acyl-CoA Dehydrogenases Allows Flavin-Ring Repositioning and Modulates Substrate Side Chain Specificity.
Stirling AJ, Gilbert SE, Conner M, Mallette E, Kimber MS, Seah SYK.
Stirling AJ, et al. Among authors: gilbert se.
Biochemistry. 2020 Oct 27;59(42):4081-4092. doi: 10.1021/acs.biochem.0c00568. Epub 2020 Oct 11.
Biochemistry. 2020.
PMID: 33040522
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